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Gene and protein analysis in AMD

Research Unit: Ocular Genetics
Primary Supervisor: Associate Professor Paul Baird
Tel: +613 9929 8613 / Email: pnb@unimelb.edu.au

Age related macular degeneration (AMD) is the leading cause of blindness in Australia. A number of genes have been identified in this disease which point to an immune role. A treatment for this disease is available but not all patients do well. This project will assess the role of genes (DNA and RNA) and changes in proteins in the serum of patients based on treatment outcome as well as in patients with different genetic profiles. You will undertake a range of molecular biology techniques including DNA, RNA and protein extraction from patient blood, use RT-PCR, RNA Seq as well as various protein techniques including 2D-PAGE, Mass Spec and bioinformatics analysis.

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