About
Professor Mingguang He
Head of Ophthalmic Epidemiology
Professor Mingguang He leads CERA’s ophthalmic epidemiology research and has a particular interest in twin studies, randomised clinical trials and imaging technology.
Professor Mingguang He
Head of Ophthalmic Epidemiology
MD, PhD, FRANZCO
Professor Mingguang He is the Professor of Ophthalmic Epidemiology at the University of Melbourne.
He undertook his medical training in China and holds a Master of Public Health degree from Johns Hopkins University in Baltimore, and PhD in ophthalmology at Moorfields Eye Hospital in London.
Professor He is a global expert in vision-related clinical and epidemiologic research. He has led some important epidemiological studies and clinical trials, including the first population-based study on myopia in China, the first population-based study on glaucoma in China, a clinical trial to prove the efficacy of increased outdoor time on myopia prevention published in JAMA 2015 and a prophylactic clinical trial on angle closure glaucoma published in Lancet 2019. His publications have attracted more than 13K citations.
He has received > $10 million in major research grants in Australia, including the prestigious NHMRC investigator Grant and Medical Research Future Fund for his research on artificial intelligence.
He founded and served as the first president of the Asia Pacific Tele-Ophthalmology Society, and is a founding council member of Asia Pacific Myopia Society and Deputy Secretary-General for Asia Pacific Academy of Ophthalmology.
Professor He is actively recruiting postdoc fellows, PhD/Master students and visiting fellows for his ongoing research projects.
Key research questions
- How can artificial intelligence-assisted screening for diabetic retinopathy and other eye diseases be applied in different care models in non-ophthalmology settings, like GP clinics, endocrinology clinics and Aboriginal medical services and other screening programs?
- What is the accuracy, cost-efficiency and acceptancy of the care models in real-world practice?
- How can we integrate existing and further evolved deep learning technology to develop and validate a clinical decision system that is able to predict disease outcomes and prognosis?
Current projects
Selected publications
My team
Key collaborators
Funding and support
Current projects
- Artificial intelligence system to detect eye and cardiovascular diseases
- Artificial intelligence-assisted screening of diabetic retinopathy as a novel point-of-care model at endocrinology clinics and Aboriginal medical services.
- Artificial intelligence in ophthalmology: from data to algorithm and real-world application
- Eye health and chronic conditions in an adult population in NSW – findings from a large-scale cohort study
Selected publications
- He M, Xiang F, Zeng Y, et al. Effect of Time Spent Outdoors at School on the Development of Myopia Among Children in China: A Randomized Clinical Trial. JAMA. 2015;314(11):1142-1148. DOI:1001/jama.2015.10803
- He M, Jiang Y, Huang S, et al. Laser peripheral iridotomy for the prevention of angle closure: a single-centre, randomised controlled trial. Lancet. 2019;393(10181):1609-1618. DOI: 1016/S0140-6736(18)32607-2
- Li Z., Keel S., Liu C., He Y., Meng W., Scheetz J., Lee P. Y., Shaw J., Ting D., Wong T., Taylor H., Chang R., He M. An Automated Grading System for Detection of Vision-Threatening Referable Diabetic Retinopathy on the Basis of Color Fundus Photographs. Diabetes care. 2018;41(12):2509-2516. DOI:2337/dc18-0147
- Keel S., Wu J., Lee P. Y., Scheetz J., He M. Visualizing Deep Learning Models for the Detection of Referable Diabetic Retinopathy and Glaucoma. JAMA ophthalmology. 2018. DOI:: 1001/jamaophthalmol.2018.6035
- Li Z., He Y., Keel S., Meng W., Chang R. T., He M. Efficacy of a Deep Learning System for Detecting Glaucomatous Optic Neuropathy Based on Color Fundus Photographs. Ophthalmology. 2018. DOI: 1016/j.ophtha.2018.01.023
See more publications
My team
- Dr Andreas Muller – Senior Research Fellow, Deputy Director of WHO Collaborating Centre at CERA
- Dr Xianwen Shang – Research Fellow and Biostatistician
- Dr Zachary Tan – Research Fellow
- Dr Lei Zhang – Senior Research Fellow
- Dr Liying Li – Research Assistant
- Mr Jason Sun – Project Consultant
- Candy Han Yue – Research Assistant
Key collaborators
- Prof Yizhi Liu, Zhongshan Ophthalmic Centre, Sun Yat-sen University
- A/Prof Angus Turner, University Western Australia and the McCusker Director of Lions Outback Vision
- Prof Tien Wong, Vitreo-Retinal Department, Singapore National Eye Centre
- Prof Paul Foster, Institute of Ophthalmology, University College London
- Prof Tin Aung, Glaucoma Department, Singapore National Eye Centre
- Prof Ian Morgan, Research School of Biology, Australian National University
- Prof David Friedman, Johns Hopkins Bloomberg School of Public Health and Wilmer Eye Institute, Johns Hopkins University
- Prof Nathan Congdon, Queen’s University Belfast, Belfast, UK
- Assoc Prof Ying Chau, Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology
Funding and support
- Medical Research Future Fund (2017-2018, 2020-2023)
- National Health & Medical Research Council, NHMRC (2020-2023, 2020-2025)
- BUPA Health Foundation (2015-2019)
- Google Impact Challenge, Australia (2017-2019)
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