Lead Researcher: Dr Alice Pébay
Neuroregeneration focuses on the study of stem cells for modelling diseases and regeneration. A stem cell is described as ‘pluripotent’, meaning that it has the potential to develop into any other type of cell in the body. We also study the cellular mechanisms involved in the genetic disease Friedreich Ataxia and aim to identify pathways to improve outcomes of neurotrauma.
Differentiation of pluripotent stem cells for ocular disease modelling
One of the major benefits of stem cells is that they can provide an endless supply of other cells for us to study in the laboratory – in our case, eye cells.
We are establishing well-characterised and efficient protocols for the maintenance and differentiation of pluripotent stem cells into various types of eye cells (in particular retinal cells), suitable for drug screening, disease modelling and potentially, transplantation.