CERA

Science and Research

DWEK: Descemetorhexis for guttatae predominant Fuchs’ Endothelial Dystrophy: A prospective, interventional case series

This study is investigating whether the DWEK procedure will successfully allow for healthy endothelial cells from the untouched, outside areas of the cornea to regenerate and heal the central cornea in patients with Fuch's endothelial dystrophy.

Overview

This study is investigating the DWEK surgical procedure – in which a small area of the diseased endothelium and Descemet’s membrane in the centre of the cornea are removed – in patients with Fuchs’ endothelial dystrophy, whose vision is degraded mainly by the build-up of the protein spots (‘guttatae’) on the endothelium, before the cornea has become significantly swollen.

The primary objective is to investigate whether the DWEK procedure will successfully allow for healthy endothelial cells from the untouched, outside areas of the cornea to regenerate and heal the central cornea in these patients.

  • Principal Investigator
Associate Professor Elaine Chong