Science and Research
Our researchers investigate the role of mitochondrial function and genetics in neurodegenerative disorders, particularly glaucoma and other diseases of the optic nerve.
Why this research is important
Our research in glaucoma will help determine if new treatment approaches that target mitochondrial function – rather than focusing on eye pressure – can help slow disease progression.
By studying the cellular and molecular changes that occur in LHON, we hope to make discoveries that will lead to treatments to prevent or treat this devastating condition.
Key research questions
- Can nuclear gene variants combine with mitochondrial DNA variants to increase disease risk in glaucoma and Parkinson’s disease?
- Investigating the protective pathways that prevent vision loss in Leber’s hereditary optic neuropathy.