Science and Research
Visual neuroscience research
Our team is focused on understanding how and why cells in the retina and optic nerve degenerate in glaucoma so we can develop earlier detection methods and targeted treatments that prevent, slow or restore vision loss.
Overview
Vision relies on healthy retinal ganglion cells. These are nerve cells that send visual information from the retina in the back of the eye through the optic nerve to the brain.
Different types of retinal ganglion cells detect different aspects of what we see, such as light and dark, colour and movement. The brain puts all of this information together to create our vision.
In glaucoma, these cells gradually die, causing permanent vision loss. At present, the only treatment for glaucoma is to lower the pressure inside the eye.
Despite treatment, retinal ganglion cells still die in a large proportion of affected individuals. For this reason, it is important to better understand why and how these cells are damaged in glaucoma, so that new and more effective treatments can be developed.
Why this research is important
By identifying the underlying processes that lead to cell death, researchers can develop treatments that target the underlying causes of the disease. This knowledge may also allow glaucoma to be detected earlier, before significant vision loss occurs – opening the door to earlier intervention and better long-term outcomes for patients.
Key research questions
- How do the retinal ganglion cell types degenerate in glaucoma?
- What is the cause of type-specific retinal ganglion cell degeneration?