About
Dr Jennifer Fan Gaskin
Senior Research Fellow, Ocular Fibrosis
Dr Jennifer Fan Gaskin is a clinician-scientist glaucoma specialist and leads CERA’s ocular fibrosis research.
Dr Jennifer Fan Gaskin
Senior Research Fellow, Ocular Fibrosis
MBChB, MD, FRANZCO
Dr Jennifer Fan Gaskin leads ocular fibrosis research at CERA and is a Consultant Ophthalmologist at The Royal Victorian Eye and Ear Hospital (RVEEH).
She was awarded the prestigious Clinical Research Training Fellowship (Health Research Council NZ) in 2007 for her Doctorate in Medicine research (Keratoconus: Novel Investigations of the Diseased Cornea).
Following vocational training, she undertook two years of glaucoma fellowships (2013–2014) in Auckland and Melbourne respectively, and was actively recruited to join the Glaucoma Unit at RVEEH and CERA.
Dr Fan Gaskin’s current research focus is on developing an effective and safe method of controlling postoperative scarring in glaucoma surgery to prevent glaucoma blindness. She is also working on preventing fibrosis in other eye diseases such as macular degeneration and proliferative vitreoretinopathy.
She is active in teaching ophthalmology registrars and glaucoma fellows at RVEEH. She has also supervised two University of Melbourne (UoM) Masters students (MPhil, MBiotech), two UoM Bachelor of Science Honours students and four UoM MD Elective students.
Dr Fan Gaskin serves on many executive and scientific boards, including the Australian and New Zealand Glaucoma Society, Glaucoma Australia, the RANZCO Scientific Programme Executive Committee and Australian Vision Research, for which she is the Secretarial Director. She is also a Glaucoma Section Editor for Clinical and Experimental Ophthalmology – currently ranked 8th in Journal Impact Factor out of 95 Ophthalmology Journals. In 2021, she was named one of Science and Technology Australia’s Superstars of STEM.
Key research questions
- How can we make glaucoma surgery safer and more effective?
- What are new methods of treating glaucoma?
Current projects
Selected publications
My team
Key collaborators
Funding and support
Current projects
Finding novel ways to reduce post-operative scarring in glaucoma patients.
While glaucoma filtration surgery is effective, the operation has a high rate of failure due to scarring. The current anti-scarring agents that are used are nonspecific, chemotherapy agents that have unfavourable risks. Our goal is to develop a more specific, less toxic, and clinically effective anti-scarring agent to improve the safety and efficacy of glaucoma surgery.
The availability of such an agent would also help improve the long-term benefit of the recently launched minimally- invasive glaucoma surgical devices. These devices are less invasive than traditional glaucoma surgery and have resulted in earlier adoption of surgery. However, it has already become evident that post-operative scarring is substantially reducing the long-term benefit of these devices and the manufacturers are actively seeking improved methods of fibrosis control.
Selected publications
- Chan EC, Zeng C, Luu C, Abbott CJ, Chan NT, Datta KK, Williamson N, Allen PH, Fan Gaskin JC. Effect of 3’,4’-dihydroxyflavonol eye drops in a rat model of dispase-induced proliferative vitreoretinopathy. Antioxidants2025, 14(12), 1414
- Pasvanis Z, Kong CK, Chan E, Fan Gaskin JC. Inhibitory Effects of 3’, 4’-Dihydroxyflavonol in a Rabbit Model of Minimally Invasive Glaucoma Surgery with PreserFlo® MicroShunt. Clin Exp Ophthalmol 2025 16;53(8):986–995
- Pasvanis Z, Kong CK, Shah MH, Chan EC, Fan Gaskin JC. 3’, 4’-Dihydroxyflavonol Inhibits Fibrotic Response in a Rabbit Model of Glaucoma Filtration Surgery. Int J Mol Sci 2024;25:10767
- Fan Gaskin JC, Bigirimana D, Kong GYX, McGuinness MB, Atik A, Liu L, Brooks AMV, Ang GS. Prospective, Randomised Controlled Trial of Cataract Surgery versus combined Cataract Surgery with insertion of iStent Inject. Ophthal Glaucoma 2024;7:326-334
My team
- Dr Elsa Chan – Research Fellow
- Ms Jemma Court – Research Assistant
Key collaborators
Funding and support
Thank you to the following organisations for their support:
- Australian Vision Research
- BrightFocus Foundation
- CASS Foundation
- University of Melbourne Annemarie Zelkin-Mankiewicz Fellowship
- Louisa Jean de Bretteville Bequest
- University of Melbourne Maurice Cantlon Memorial Fund
- Cuthbertson Foundation
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