Science and Research
Cellular reprogramming research
Our researchers use cell reprogramming and stem cell technologies to better understand and develop treatments for eye diseases, with the goal of regenerating cells in the retina.
Why this research is important
Many degenerative retinal disorders are characterised by the loss of retinal cells, resulting in vision loss and blindness. These diseases affect millions of patients worldwide and cause a significant socio-economic burden on our healthcare system. Currently, there is no effective way to cure blindness once the retinal cells are lost.
Our research aims to develop regenerative therapy for the retina, which has the very real prospect of replacing the retinal cell losses and help restore vision in these patients.
Key research questions
- How do we generate human retinal cells in the lab using stem cell technologies?
- Can we regenerate the retina to treat blindness caused by retinal degenerative diseases?
- Can we use new gene editing technology to develop gene therapy for inherited retinal diseases?
- What are the signals that support retinal cells for healthy vision?