Science and Research
Gene therapy research
CERA is leading world-first research into gene therapies that could halt or even reverse vision loss in patients with conditions including inherited retinal diseases and glaucoma.
Why this research is important
Millions of working-age people worldwide are affected by inherited retinal diseases like retinitis pigmentosa, macular dystrophy, or a range of rarer genetic conditions. More than 200 genes are known to be associated with retinal diseases.
These conditions are currently considered untreatable. Gene therapy brings new hope that we may be able to stop the progression of vision loss for some patients, or even one day restore some sight.
As research progresses, we may also develop techniques that can be applied to more common eye diseases with a genetic basis such as age-related macular degeneration.
Key research questions
- Can we find novel therapies gene therapies to find a cure for inherited retinal degeneration?
- Can we halt progression of specific inherited retinal diseases with specific novel therapies, e.g. gene therapy?
- Can gene therapy be used to treat patients with glaucoma whose vision is deteriorating despite conventional treatment to lower the eye pressure?
- Can we regenerate the damaged optic nerve to achieve useful restoration of vision?
Gene therapy explained
In this video, learn about CERA’s world-first research into gene therapies that could halt or even reverse vision loss in patients with conditions such as inherited retinal diseases and glaucoma.